PF-04363467 HYDROCHLORIDE

Code: PZ0354-25MG D2-231

Biochem/physiol Actions

PF-4363467 hydrochloride is a Dopamine D3/D2 receptor antagonist. PF-4363467 has 100-fold selectivity for D3 with a Ki value of 3.1 nM for D3R compare...


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€369.60 25MG
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Biochem/physiol Actions

PF-4363467 hydrochloride is a Dopamine D3/D2 receptor antagonist. PF-4363467 has 100-fold selectivity for D3 with a Ki value of 3.1 nM for D3R compared to a Ki value of 692 nM for D2R and high selectivity for D3R compared to other biogenic amine receptors. PF-4363467 attenuated opioid drug-seeking behavior in a rat model of addiction without causing the extrapyramidal symptoms often associated with D2R antagonism.

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Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
manufacturer/tradenamePfizer®
originatorPfizer
Quality Level100
SMILES string[H]Cl.CC1=CC([C@H]2CN(CC)CCO2)=CC=C1NS(C3=CC=C(C(C)C)C=C3)(=O)=O
solubilityH2O: 3 mg/mL, clear (warmed)
storage temp.room temp
Cas Number2040055-81-8
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